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About
I am the youngest of 8 children, have many nieces and nephews, as well as 5 great nephews. I am a fan of movies, cooking, craft beer, and LEGO. I began a PhD program in Biochemistry and Molecular Genetics at the University of Virginia in Fall of 2019. I then joined the lab of Dave Kashatus in January of 2020.
Research Summary
Elucidating the ability of oncogenes to regulate lipid droplet homeostasis and the influence this regulation has on the pathophysiology of cancer cells.
Education
University of Virginia
Biochemistry and Molecular GeneticsPhD
2019 / 08 - Present
Publications
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RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal
10.1016/j.celrep.2021.109451
Syed S. Hussain; Tuyet-Minh Tran; Timothy B. Ware; Melissa A. Luse; Christopher T. Prevost; Ashley N. Ferguson; Jennifer A. Kashatus; Ku-Lung Hsu; David F. Kashatus
An intellectual disability-associated missense variant in TRMT1 impairs tRNA modification and reconstitution of enzymatic activity
10.1002/humu.23976
Zhang, Kejia; Lentini, Jenna M; Prevost, Christopher T; Hashem, Mais O; Alkuraya, Fowzan S; Fu, Dragony
(2020/03/)
Biallelic variants in CTU2 cause DREAM-PL syndrome and impair thiolation of tRNA wobble U34
https://doi.org/10.1002/humu.23870
Shaheen, Ranad; Mark, Paul; Prevost, Christopher T.; AlKindi, Adila; Alhag, Ahmad; Estwani, Fatima; Al-Sheddi, Tarfa; Alobeid, Eman; Alenazi, Mona M.; Ewida, Nour; Ibrahim, Niema; Hashem, Mais; Abdulwahab, Firdous; Bryant, Emily M.; Spinelli, Egidio; Millichap, John; Barnett, Sarah S.; Kearney, Hutton M.; Accogli, Andrea; Scala, Marcello; Capra, Valeria; Nigro, Vincenzo; Fu, Dragony; Alkuraya, Fowzan S.
Human Mutation
(2019)
The influence of mitochondrial dynamics on mitochondrial genome stability
10.1007/s00294-017-0717-4
Prevost, Christopher T.; Peris, Nicole; Seger, Christina; Pedeville, Deanna R.; Wershing, Kathryn; Sia, Elaine A.; Sia, Rey A. L.
Current Genetics
(2018)
Roles for the Rad27 Flap Endonuclease in Mitochondrial Mutagenesis and Double-Strand Break Repair in Saccharomyces cerevisiae
10.1534/genetics.116.195149
Nagarajan, Prabha; Prevost, Christopher T; Stein, Alexis; Kasimer, Rachel; Kalifa, Lidza; Sia, Elaine A
Genetics
(2017)
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