RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal

10.1016/j.celrep.2021.109451

Syed S. Hussain; Tuyet-Minh Tran; Timothy B. Ware; Melissa A. Luse; Christopher T. Prevost; Ashley N. Ferguson; Jennifer A. Kashatus; Ku-Lung Hsu; David F. Kashatus

RalA and RalB relocalization to depolarized mitochondria depends on clathrin-mediated endocytosis and facilitates TBK1 activation

10.1371/journal.pone.0214764

Sarah R. Pollock, Austin R. Schinlever, Ali Rohani, Jennifer A. Kashatus, David F. Kashatus

MDVs: Spare the SOD and Spoil the Bug

10.1016/j.chom.2018.10.013

Syed Saad Hussain; David F. Kashatus

PIM kinases alter mitochondrial dynamics and chemosensitivity in lung cancer

10.1038/s41388-020-1168-9

Shailender S. Chauhan; Rachel K. Toth; Corbin C. Jensen; Andrea L. Casillas; David F. Kashatus; Noel A. Warfel
Oncogene

The regulation of tumor cell physiology by mitochondrial dynamics

10.1016/j.bbrc.2017.06.192

David F. Kashatus

Dynamin-Related Protein 1 Deficiency Promotes Recovery from AKI

10.1681/ASN.2017060659

Mitochondrial dynamics in cancer stem cells

10.1007/s00018-021-03773-2

Dane T. Sessions; David F. Kashatus
Cellular and Molecular Life Sciences

Segmented cell analyses to measure redox states of autofluorescent NAD(P)H, FAD & Trp in cancer cells by FLIM

10.1038/s41598-017-18634-x

Horst Wallrabe; Zdenek Svindrych; Shagufta R. Alam; Karsten H. Siller; Tianxiong Wang; David Kashatus; Song Hu; Ammasi Periasamy
Scientific Reports

Mitochondrial protein S-nitrosation protects against ischemia reperfusion-induced denervation at neuromuscular junction in skeletal muscle

10.1016/j.freeradbiomed.2018.02.006

Rebecca J. Wilson; Joshua C. Drake; Di Cui; Bevan M. Lewellen; Carleigh C. Fisher; Mei Zhang; David F. Kashatus; Lisa A. Palmer; Michael P. Murphy; Zhen Yan

Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy

10.1016/j.mito.2017.12.008

Rebecca J. Wilson; Joshua C. Drake; Di Cui; Mei Zhang; Heather M. Perry; Jennifer A. Kashatus; Christine M. Kusminski; Philipp E. Scherer; David F. Kashatus; Mark D. Okusa; Zhen Yan

Mito Hacker: a set of tools to enable high-throughput analysis of mitochondrial network morphology

10.1038/s41598-020-75899-5

Ali Rohani; Jennifer A. Kashatus; Dane T. Sessions; Salma Sharmin; David F. Kashatus
Scientific Reports (2020)

Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth.

10.1016/j.celrep.2019.07.031

Sarbajeet Nagdas; Jennifer A. Kashatus; Aldo Nascimento; Syed S. Hussain; Riley E. Trainor; Sarah R. Pollock; Sara J. Adair; Alex D. Michaels; Hiromi Sesaki; Edward B. Stelow; Todd W. Bauer; David F. Kashatus
(2019-08-13)

Label-free quantification of intracellular mitochondrial dynamics using dielectrophoresis

Rohani, Ali; Moore, John H; Kashatus, Jennifer A; Sesaki, Hiromi; Kashatus, David F; Swami, Nathan S
Analytical chemistry (2017)

The interplay between oncogenic signaling networks and mitochondrial dynamics

Nagdas, Sarbajeet; Kashatus, David F
Antioxidants (2017)

High‐throughput detection and quantification of mitochondrial fusion through imaging flow cytometry

Nascimento, Aldo; Lannigan, Joanne; Kashatus, David
Cytometry Part A (2016)

Restraining the divider: a Drp1-phospholipid interaction inhibits Drp1 activity and shifts the balance from mitochondrial fission to fusion

Kashatus, David F
Molecular cell (2016)

Erk2 Phosphorylation of Drp1 Promotes Mitochondrial Fission and MAPK-Driven Tumor Growth.

10.1016/j.molcel.2015.01.002

Jennifer A. Kashatus; Aldo Nascimento; Lindsey J. Myers; Annie Sher; Frances L. Byrne; Kyle L. Hoehn; Christopher M. Counter; David F. Kashatus
Molecular Cell (2015-02-05)

Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth

Kashatus, Jennifer A; Nascimento, Aldo; Myers, Lindsey J; Sher, Annie; Byrne, Frances L; Hoehn, Kyle L; Counter, Christopher M; Kashatus, David F
Molecular cell (2015)

Mitochondrial control by DRP1 in brain tumor initiating cells

Xie, Qi; Wu, Qiulian; Horbinski, Craig M; Flavahan, William A; Yang, Kailin; Zhou, Wenchao; Dombrowski, Stephen M; Huang, Zhi; Fang, Xiaoguang; Shi, Yu
Nature neuroscience (2015)

Ral GTPases in tumorigenesis: emerging from the shadows

Kashatus, David F
Experimental cell research (2013)

Targeting eNOS in pancreatic cancer

Lampson, Benjamin L; Kendall, S DiSean; Ancrile, Brooke B; Morrison, Meghan M; Shealy, Michael J; Barrientos, Katharine S; Crowe, Matthew S; Kashatus, David F; White, Rebekah R; Gurley, Susan B
Cancer research (2012)

RALA and RALBP1 regulate mitochondrial fission at mitosis.

10.1038/ncb2310

David F. Kashatus; Kian-Huat Lim; Donita C. Brady; Nicole L. K. Pershing; Adrienne D. Cox; Christopher M. Counter
Nature Cell Biology (2011-09)

RALA and RALBP1 regulate mitochondrial fission at mitosis

Kashatus, David F; Lim, Kian-Huat; Brady, Donita C; Pershing, Nicole LK; Cox, Adrienne D; Counter, Christopher M
Nature cell biology (2011)

Breaking up is hard to do: RalA, mitochondrial fission and cancer

Kashatus, David F; Counter, Christopher M
Small GTPases (2011)

Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA

Lim, Kian-Huat; Brady, Donita C; Kashatus, David F; Ancrile, Brooke B; Der, Channing J; Cox, Adrienne D; Counter, Christopher M
Molecular and cellular biology (2010)

cPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatis

Vignola, Mark J; Kashatus, David F; Taylor, Gregory A; Counter, Christopher M; Valdivia, Raphael H
Journal of Biological Chemistry (2010)

Ral activation promotes melanomagenesis

Zipfel, Patty A; Brady, Donita C; Kashatus, David F; Ancrile, Brooke D; Tyler, Douglas S; Counter, Christopher M
Oncogene (2010)

A role for eNOS in oncogenic Ras-driven cancer

Kashatus, David F; Counter, Christopher M
(2010)

Tumour maintenance is mediated by eNOS

Lim, Kian-Huat; Ancrile, Brooke B; Kashatus, David F; Counter, Christopher M
Nature (2008)

Expression of nuclear factor-kappaB family proteins in hepatocellular carcinomas

O’Neil, Bert H; Bůžková, Petra; Farrah, Hillary; Kashatus, David; Sanoff, Hanna; Goldberg, Richard M; Baldwin, Albert S; Funkhouser, William K
Oncology (2007)

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

Kashatus, David; Cogswell, Patricia; Baldwin, Albert S
Genes & development (2006)

The nuclear factor κB subunits RelA/p65 and c-Rel potentiate but are not required for Ras-induced cellular transformation

Hanson, Julie L; Hawke, Noel A; Kashatus, David; Baldwin, Albert S
Cancer research (2004)

NF-κB and IκBα are found in the mitochondria: evidence for regulation of mitochondrial gene expression by NF-κB

Cogswell, Patricia C; Kashatus, David F; Keifer, Jayne A; Guttridge, Denis C; Reuther, Julie Y; Bristow, Cindy; Roy, Sophie; Nicholson, Donald W; Baldwin Jr, Albert S
Journal of Biological Chemistry (2003)

The p65/RelA subunit of NF-κB suppresses the sustained, antiapoptotic activity of Jun kinase induced by tumor necrosis factor

Reuther-Madrid, Julie Y; Kashatus, David; Chen, Shaoqiong; Li, Xiong; Westwick, John; Davis, Roger J; Earp, H Shelton; Wang, Cun-Yu; Baldwin Jr, Albert S
Molecular and cellular biology (2002)